NeuroRein
中文
Clinical Applications

Bringing BCI into the clinic

Non-invasive monitoring and assessment for disorders of consciousness — objective, quantifiable tools for the clinic.

NeuroRein UWS
01Background

From coma to emergence — one continuous spectrum

The clinical spectrum of DoC
Coma
ArousalAbsent
AwarenessAbsent

No sleep-wake cycle

UWSDissociated
ArousalPresent
AwarenessAbsent

Eyes open, no command following

MCS−
ArousalPresent
AwarenessLow

Visual pursuit / emotional response

MCS+
ArousalPresent
AwarenessHigh

Stable command following

E-MCS
ArousalPresent
AwarenessFunctional

Functional communication

Arousal without awareness · seemingly awake, in fact unconscious
500K+
new cases / year
2M+
living patients
30–40%
misdiagnosis rate
Three clinical dilemmas today

Subjective

CRS-R scale misses residual awareness

Not home-based

fMRI / PET can't enter the home

Unmet needs

Families long for communication & feedback

02System Architecture

One core platform, three extending ends

Patient Bedside
Core platform
Developed + real-patient tested
Family App
Prototype

De-identified data · Care guidance · Alerts

Medical Institution
Designed

Remote review · Structured reports

Research
Built

Group statistics · Offline deep decoding

data.neurorein.com

Data acquisition → Clinical decision → Family participation → Research iteration

03Patient Bedside

Home-based multimodal monitoring & assessment

EEGPhysiological signals

EEG at the core, physiology assisting — passive, continuous, quantified

Eight angles of real-time monitoring
Physiological stability
Sleep-wake cycle
Epileptiform discharge
Consciousness level
0–10
Comfort & stress
Autonomic function
Early infection alert
Environmental response
Five stimulation paradigms
Auditory oddball
MMN
Name calling
P300
Olfactory stimulus
P3
News feedback
N400
Ambient sound
Familiarity
Bedside software UI
Patient bedside software screenshot
Patient bedside software screenshot
Patient bedside software screenshot
Patient bedside software screenshot
Offline operationPassive monitoringUnattendedInternational standard format · local storage · traceable
04First Real-Patient Test

22 hours overnight, closing the full loop

UWS-001
Mr. Liu
50+ y/o8 years UWSJul 2026 · at home
22-hour overnight monitoring
Validation results
System validation
100%Effective channels
>95%EEG quality (OAR)
4.5hLongest continuous run
Patient assessment
22hCircadian rhythm
Sleep-wake cycle
Autonomic function
Consciousness level · circadian rhythm
First real-patient test scene
Deep neurophysiological analysis
Spectral analysisBrain-network connectivityEEG microstatesTime-frequency
05Ethics & Data Security

Non-invasive · Compliant · Secure

Non-invasive

Scalp electrodesNo medicationPassive acquisitionNo intervention

Ethical

Ethics review in progressDigital informed consentWithdrawable consentNo camera, no recording

Data security

De-identified dual IDAES-256 encryptionTiered accessTamper-proof audit log
Compliance & standardsPersonal Information Protection LawData Security LawGB/T 39725
06Progress & Roadmap

From bedside to the full care chain

Current progress
  1. Bedside
    Completed
  2. Family App
    Prototype
  3. Medical Institution
    Designed
  4. Research
    Built
Roadmap
  1. Near-term12 months
    Family App & Medical Institution beta
  2. Mid-term1–2 years
    Medical Institution release + group statistics
  3. Long-term
    Registration + insurance pilot + full chain
07Contact Us

Welcome families of patients to contact us

FREE

Devices & services · fully free

Patient info
AgeGenderDiagnosisDurationCause
Family info
NamePhone / WeChat
Free consultation

Currently in the clinical research phase

08Disclaimer

Disclaimer

Disclaimer

NeuroRein_UWS is a non-invasive brain-computer interface monitoring and assessment platform developed by Hangzhou Yuyi Technology; the current version is for clinical research use only, has not yet obtained medical device registration, and its ethics review is still in progress. The system passively and non-invasively collects EEG and physiological signals, and serves only to assist monitoring and assessment of consciousness and brain-function trends — it performs no therapeutic intervention. Its outputs are for doctors' clinical reference only, do not constitute a clinical diagnosis, and do not replace the independent judgment of a licensed doctor. All use follows data-protection measures including de-identification, informed consent, encryption, and audit logging.